Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS)-Reference-Cited by-同舟云学术

Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS)

Published:2017 Issue:4 Volume:9 Page:290-302
ISSN:1757-9694
Container-title:Integrative Biology
language:en
Short-container-title:Integr. Biol.

Author:

Maass Christian¹²³⁴^ORCID,Stokes Cynthia L.⁵⁶⁴,Griffith Linda G.¹²³⁴,Cirit Murat¹²³⁴

Affiliation:

1. Department of Biological Engineering

2. Massachusetts Institute of Technology

3. Cambridge

4. USA

5. Stokes Consulting

6. Redwood City

Abstract

Multi-functional scaling is a mechanistic framework to design integrated microphysiological systems for pharmacological applications.

Funder

Defense Advanced Research Projects Agency

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Link

http://pubs.rsc.org/en/content/articlepdf/2017/IB/C6IB00243A

Reference74 articles.

1. Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling

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3. Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function

4. A Human Breathing Lung-on-a-Chip

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