A gold-catalysed imine–propargylamine cascade sequence: synthesis of 3-substituted-2,5-dimethylpyrazines and the reaction mechanism-Reference-Cited by-同舟云学术

A gold-catalysed imine–propargylamine cascade sequence: synthesis of 3-substituted-2,5-dimethylpyrazines and the reaction mechanism

Published:2014 Issue:35 Volume:50 Page:4567-4570
ISSN:1359-7345
Container-title:Chem. Commun.
language:en
Short-container-title:Chem. Commun.

Author:

Alcaide Benito¹²³⁴⁵,Almendros Pedro⁶⁷⁸,Alonso José M.¹²³⁴⁵,Fernández Israel²⁴⁵⁹,Gómez-Campillos Gonzalo¹²³⁴⁵,Torres M. Rosario¹⁰⁴⁵⁹

Affiliation:

1. Grupo de Lactamas y Heterociclos Bioactivos

2. Departamento de Química Orgánica

3. Unidad Asociada al CSIC

4. Facultad de Química

5. Universidad Complutense de Madrid

6. Instituto de Química Orgánica General

7. IQOG-CSIC

8. 28006-Madrid, Spain

9. 28040-Madrid, Spain

10. CAI Difracción de Rayos X

Abstract

The gold-catalysed coupling reaction between propargylamine-derived imines and propargylamine exclusively afforded pyrazines.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CC/C4CC01485E

Reference15 articles.

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2. M.-P. Cabal , Six-Membered Heterocycles: 1,2-, 1,3-, and 1,4-Diazines: and Related Systems , in Modern Heterocyclic Chemistry , ed. J. Álvarez-Builla , J. J. Vaquero and J. Barluenga , Wiley-VCH , Weinheim, Germany , 2011 , vol. 1, pp. 1683–1776

3. Analysis of Volatile Flavor Components in Roasted Peanuts Using Supercritical Fluid Extraction and Gas Chromatography−Mass Spectrometry

4. Structure and synthesis of tetrasubstituted pyrazines in ants in the genus

5. Synthesis and antitumor activity of indolylpyrimidines: Marine natural product meridianin D analogues

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