A ruthenium–oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy-Reference-Cited by-同舟云学术

A ruthenium–oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy

Published:2022 Issue:1 Volume:3 Page:85-95
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

McKenzie Luke K.¹²^ORCID,Flamme Marie¹²³^ORCID,Felder Patrick S.²^ORCID,Karges Johannes²^ORCID,Bonhomme Frederic⁴^ORCID,Gandioso Albert²^ORCID,Malosse Christian⁵,Gasser Gilles²^ORCID,Hollenstein Marcel¹^ORCID

Affiliation:

1. Institut Pasteur, Department of Structural Biology and Chemistry, Laboratory for Bioorganic Chemistry of Nucleic Acids, CNRS UMR3523, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France

2. Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005 Paris, France

3. Université de Paris, 12 rue de l'École de Médecine, 75006 Paris, France

4. Institut Pasteur, Department of Structural Biology and Chemistry, Unité de Chimie Biologique Epigénétique, UMR CNRS 3523, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France

5. Institut Pasteur, Mass Spectrometry for Biology Unit, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France

Abstract

Ruthenium complexes have emerged as a promising class of compounds for use as photosensitizers in photodynamic therapy. Direct conjugation to aptamers enhances their therapeutic usefulness by conveying specificity to Ru-mediated PDT.

Funder

Agence Nationale de la Recherche

Fondation ARC pour la Recherche sur le Cancer

Institut Pasteur

Fondation de l'Avenir pour la Recherche Médicale Appliquée

Centre de Compétences Nanosciences Ile-de-France

Joe W. and Dorothy Dorsett Brown Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

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