Optical control of GPR40 signalling in pancreatic β-cells

Author:

Frank James Allen12345ORCID,Yushchenko Dmytro A.67859ORCID,Fine Nicholas H. F.1011121314ORCID,Duca Margherita12345ORCID,Citir Mevlut6785,Broichhagen Johannes12345ORCID,Hodson David J.1011121314ORCID,Schultz Carsten678515,Trauner Dirk12345ORCID

Affiliation:

1. Department of Chemistry

2. Center for Integrated Protein Science

3. Ludwig Maximilians University Munich

4. 81377 Munich

5. Germany

6. European Molecular Biology Laboratory (EMBL)

7. Cell Biology & Biophysics Unit

8. 69117 Heidelberg

9. Institute of Organic Chemistry and Biochemistry

10. Institute of Metabolism and Systems Research (IMSR)

11. University of Birmingham

12. Birmingham

13. UK

14. Centre for Endocrinology, Diabetes and Metabolism

15. Dept. of Physiology and Pharmacology

Abstract

Fatty acids activate GPR40 and K+ channels to modulate β-cell function.

Funder

Deutsche Forschungsgemeinschaft

Wellcome Trust

Novo Nordisk UK Research Foundation

Medical Research Council

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference40 articles.

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