Optical control of GPR40 signalling in pancreatic β-cells-Reference-Cited by-同舟云学术

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Optical control of GPR40 signalling in pancreatic β-cells

Published:2017 Issue:11 Volume:8 Page:7604-7610
ISSN:2041-6520
Container-title:Chem. Sci.
language:en
Short-container-title:Chem. Sci.

Author:

Frank James Allen¹²³⁴⁵^ORCID,Yushchenko Dmytro A.⁶⁷⁸⁵⁹^ORCID,Fine Nicholas H. F.¹⁰¹¹¹²¹³¹⁴^ORCID,Duca Margherita¹²³⁴⁵^ORCID,Citir Mevlut⁶⁷⁸⁵,Broichhagen Johannes¹²³⁴⁵^ORCID,Hodson David J.¹⁰¹¹¹²¹³¹⁴^ORCID,Schultz Carsten⁶⁷⁸⁵¹⁵,Trauner Dirk¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Center for Integrated Protein Science

3. Ludwig Maximilians University Munich

4. 81377 Munich

5. Germany

6. European Molecular Biology Laboratory (EMBL)

7. Cell Biology & Biophysics Unit

8. 69117 Heidelberg

9. Institute of Organic Chemistry and Biochemistry

10. Institute of Metabolism and Systems Research (IMSR)

11. University of Birmingham

12. Birmingham

13. UK

14. Centre for Endocrinology, Diabetes and Metabolism

15. Dept. of Physiology and Pharmacology

Abstract

Fatty acids activate GPR40 and K⁺ channels to modulate β-cell function.

Funder

Deutsche Forschungsgemeinschaft

Wellcome Trust

Novo Nordisk UK Research Foundation

Medical Research Council

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC01475A

Reference40 articles.

1. Arachidonic acid and ion channels: an update

2. Mechanisms of action of docosahexaenoic acid in the nervous system

3. Complex Pharmacology of Free Fatty Acid Receptors

4. Polyunsaturated Fatty Acid Modulation of Voltage-Gated Ion Channels

5. IUPAC Gold Book – Fatty Acids, ed. A. D. McNaught and A. Wilkinson, Blackwell Scientific Publications, Oxford, 2nd edn, 1997

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