Ionic liquid-coated lipid nanoparticles increase siRNA uptake into CNS targets-Reference-Cited by-同舟云学术

Ionic liquid-coated lipid nanoparticles increase siRNA uptake into CNS targets

Published:2024 Issue: Volume: Page:
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Khare Purva¹,Edgecomb Sara X.²,Hamadani Christine M.²^ORCID,Conway James F.³,Tanner Eden E. L.²^ORCID,S Manickam Devika¹^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, 453 Mellon Hall, Pittsburgh, PA 15282, USA

2. Department of Chemistry and Biochemistry, The University of Mississippi, MS, USA

3. Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

Abstract

Ionic liquid (IL)-coated LNPs increase siRNA uptake into brain endothelial cells and motor neurons and lesser plasma proteins compared to standard LNPs.

Funder

Duquesne University

Pharmaceutical Research and Manufacturers of America Foundation

University of Mississippi

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NA/D3NA00699A

Reference107 articles.

1. R.Cross , Without these lipid shells, there would be no mRNA vaccines for COVID-19 , https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8

2. F. N. RELEASE, FDA Approves First COVID-19 Vaccine , https://www.fda.gov/news-events/press-announcements/fda-approves-first-covid-19-vaccine

3. Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

4. Lipid nanoparticle-mediated drug delivery to the brain

5. The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Liposomal Nanomaterials: A Rising Star in Glioma Treatment;International Journal of Nanomedicine;2024-07