A biocatalytic redox cascade approach for one-pot deracemization of carboxyl-substituted tetrahydroisoquinolines by stereoinversion
Author:
Affiliation:
1. Institute of Bioengineering
2. College of Chemical and Biological Engineering
3. Zhejiang University
4. Hangzhou
5. People's Republic of China
6. Tongli Biomedical Co.
7. Ltd
8. Zhangjiagang
Abstract
We describe a biocatalytic redox cascade reaction for one-pot enantioselective synthesis of (S)-carboxyl substituted tetrahydroisoquinolines.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/GC/C9GC02795E
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4. Diversity-oriented synthesis of medicinally important 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives and higher analogs
5. Novel strategies for catalytic asymmetric synthesis of C1-chiral 1,2,3,4-tetrahydroisoquinolines and 3,4-dihydrotetrahydroisoquinolines
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