Indicator displacement assays (IDAs): the past, present and future

Author:

Sedgwick Adam C.1234ORCID,Brewster James T.1234ORCID,Wu Tianhong56789,Feng Xing56789,Bull Steven D.1101112ORCID,Qian Xuhong1314151617,Sessler Jonathan L.1234ORCID,James Tony D.1101112ORCID,Anslyn Eric V.1234ORCID,Sun Xiaolong56789ORCID

Affiliation:

1. Department of Chemistry

2. The University of Texas at Austin

3. Austin

4. USA

5. The Key Laboratory of Biomedical Information Engineering of Ministry of Education

6. School of Life Science and Technology

7. Xi’an Jiaotong University

8. Xi’an

9. P. R. China

10. University of Bath

11. Bath

12. UK

13. State Key Laboratory of Bioreactor Engineering

14. Shanghai Key Laboratory of Chemical Biology

15. School of Pharmacy

16. East China University of Science and Technology

17. Shanghai 200237

Abstract

Indicator displacement assays (IDAs) offer a unique and innovative approach to molecular sensing. This Tutorial review discusses the basic concepts of each IDA strategy and illustrates their use in sensing applications.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shaanxi Province

Welch Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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