Synthesis of CHF2-substituted 3-azabicyclo[3.1.0]hexanes by photochemical decomposition of CHF2-pyrazolines-Reference-Cited by-同舟云学术

Synthesis of CHF2-substituted 3-azabicyclo[3.1.0]hexanes by photochemical decomposition of CHF2-pyrazolines

Published:2018 Issue:10 Volume:8 Page:5114-5118
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zheng Yang¹²³⁴⁵,Yu Xinling¹²³⁴⁵,Lv Songyang¹²³⁴⁵,Mykhailiuk Pavel K.⁶⁷⁸⁹¹⁰^ORCID,Ma Qiang¹²³⁴⁵,Hai Li¹²³⁴⁵,Wu Yong¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Drug-Targeting of Education Ministry

2. Department of Medicinal Chemistry

3. West China School of Pharmacy

4. Sichuan University

5. Chengdu 610041

6. Enamine Ltd.

7. 01103 Kyiv

8. Ukraine

9. Taras Shevchenko National University of Kyiv Chemistry Department

10. 01601 Kyiv

Abstract

A general and efficient method has been developed to synthesize CHF₂-substituted 3-azabicyclo[3.1.0]hexane derivatives via photochemical decomposition of CHF₂-pyrazolines.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C7RA13141K

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4. Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor Antagonists

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