Cell-penetrating peptide modified AIE polymeric nanoparticles by miniemulsion polymerization and application for cell fluorescence imaging

Author:

Hu Yaxin12345,Liang Xiaoqin12345,Zhuang Zeyan67895,Cao Zhihai12345ORCID,Qi Qi12345,Wang Yijia12345,Mi Yifang12345,Zhao Zujin67895,Cui Qinmin1011125

Affiliation:

1. Key Laboratory of Advanced Textile Materials and Manufacturing Technology and Engineering Research Center for Eco-Dyeing & Finishing of Textiles

2. Ministry of Education

3. Zhejiang Sci-Tech University

4. Hangzhou 310018

5. China

6. State Key Laboratory of Luminescent Materials and Devices

7. Center for Aggregation-Induced Emission

8. South China University of Technology

9. Guangzhou 510640

10. School of Pharmacy

11. Hangzhou Medical College

12. Hangzhou 310053

Abstract

AIE polymeric nanoparticles surface-modified with HIV Tat peptides for cell fluorescence imaging are efficiently prepared through miniemulsion polymerization, carbodiimide reaction, and thiol-maleimide click reaction in sequence.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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