Targeted isolation of two disesquiterpenoid macrocephadiolides A and B from Ainsliaea macrocephala using a molecular networking-based dereplication strategy-Reference-Cited by-同舟云学术

Targeted isolation of two disesquiterpenoid macrocephadiolides A and B from Ainsliaea macrocephala using a molecular networking-based dereplication strategy

Published:2020 Issue:12 Volume:7 Page:1481-1489
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Ren Yong-Mei¹²³⁴⁵^ORCID,Zhou Shuai-Zhen¹²³⁴⁵,Zhang Tian⁶⁷⁸⁹⁵,Qian Meijia¹⁰¹¹¹²¹³⁵,Zhang Rui¹²³⁴⁵,Yao Sheng¹²³⁴⁵,Zhu Hong¹⁰¹¹¹²¹³⁵,Tang Chunping¹²³⁴⁵^ORCID,Lin Ligen⁶⁷⁸⁹⁵^ORCID,Ye Yang¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Drug Research and Natural Products Chemistry Department

2. Shanghai Institute of Materia Medica

3. Chinese Academy of Sciences

4. Shanghai 201203

5. China

6. State Key Laboratory of Quality Research in Chinese Medicine

7. Institute of Chinese Medical Sciences

8. University of Macau

9. Taipa

10. Institute of Pharmacology and Toxicology

11. College of Pharmaceutical Sciences

12. Zhejiang University

13. Hangzhou

Abstract

Two novel dimeric sesquiterpenoids with potent anti-inflammatory activity were characterized from Ainsliaea macrocephala through a molecular networking-based dereplication strategy.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00030B

Reference34 articles.

1. The Renaissance of Natural Products as Drug Candidates

2. Natural products in drug discovery