Universal point-of-care detection of proteins based on proximity hybridization-mediated isothermal exponential amplification-Reference-Cited by-同舟云学术

Universal point-of-care detection of proteins based on proximity hybridization-mediated isothermal exponential amplification

Published:2022 Issue:8 Volume:147 Page:1709-1715
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Tang Zibin¹^ORCID,Zhao Wenyong²^ORCID,Deng Yuling¹^ORCID,Sun Yuanzhong¹,Qiu Cailing³^ORCID,Wu Binhua⁴,Bao Juan¹^ORCID,Chen Zhangquan¹^ORCID,Yu Luxin¹^ORCID

Affiliation:

1. School of Medical Technology, Guangdong Medical University, Dongguan 523808, China

2. Faculty of Forensic Medicine, School of Basic Medicine, Guangdong Medical University, Dongguan 523808, China

3. Department of Medical Laboratory, Dalang Hospital of Dongguan, Dongguan 523770, China

4. Marine Biomedical Research Institute of Guangdong Medical University, Zhanjiang, 524023, China

Abstract

A lateral flow biosensor has been fabricated for protein detection based on a protein-to-DNA signal transducer, isothermal exponential amplification and catalytic hairpin assembly with high sensitivity and specificity.

Funder

Science and Technology Planning Project of Guangdong Province

Guangdong Medical Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D1AN02245H

Reference26 articles.

1. Toward sensitive, quantitative point-of-care testing (POCT) of protein markers: miniaturization of a homogeneous time-resolved fluoroimmunoassay for prostate-specific antigen detection

2. Development of an Aptamer-Based Lateral Flow Assay for the Detection of C-Reactive Protein Using Microarray Technology as a Prescreening Platform