Understanding stress-induced disorder and breakage in organic crystals: beyond crystal structure anisotropy

Author:

Schneider-Rauber Gabriela1ORCID,Arhangelskis Mihails2ORCID,Goh Wei-Pin3,Cattle James3,Hondow Nicole3,Drummond-Brydson Rik3,Ghadiri Mojtaba3,Sinha Kushal4,Ho Raimundo4,Nere Nandkishor K.4,Bordawekar Shailendra4,Sheikh Ahmad Y.4ORCID,Jones William1ORCID

Affiliation:

1. Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK

2. Faculty of Chemistry, University of Warsaw, 1 Pasteura Street, Warsaw, 02-093, Poland

3. School of Chemical and Process Engineering, University of Leeds, Leeds, LS2 9JT, UK

4. Process Research and Development, AbbVie, Inc., North Chicago, IL, USA

Abstract

Crystal engineering has advanced the strategies of design and synthesis of organic solids with the main focus being on customising the properties of the materials.

Funder

Cambridge Overseas Trust

AbbVie

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference73 articles.

1. J.Wouters and L.Quere , Pharmaceutical Salts and Co-crystals , The Royal Society of Chemistry , Cambridge , 2012

2. J.Bernstein , Polymorphism in Molecular Crystals , Oxford University Press , Oxford , 2nd edn, 2013

3. H. G.Brittain , Polymorphism in Pharmaceutical Solids , Informa Healthcare , New York , 2009

4. D.Braga and F.Grepioni , Making crystals by design: methods, techniques and applications , Wiley , Weinheim , 2007

5. S. R.Byrn , R. R.Pfeiffer and J. G.Stowell , Solid-state Chemistry of Drugs , Academic Press , New York , 1999

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