Experimental and computational insights into the mechanism of FLP mediated selective C–F bond activation-Reference-Cited by-同舟云学术

Experimental and computational insights into the mechanism of FLP mediated selective C–F bond activation

Published:2023 Issue:5 Volume:14 Page:1291-1300
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Gupta Richa¹,Csókás Dániel¹,Lye Kenneth¹,Young Rowan D.¹²^ORCID

Affiliation:

1. Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore

2. School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, 4072, Queensland, Australia

Abstract

A combined computational and experimental study reveals the mechanism for selective C–F activation by frustrated Lewis pairs (FLP) comprising of B(C6F5)3(BCF) and 2,4,6-triphenylpyridine (TPPy), P(o-Tol)3or tetrahydrothiophene (THT).

Funder

Agency for Science, Technology and Research

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D2SC05632A

Reference56 articles.

1. Picking One out of Three: Selective Single C−F Activation in Trifluoromethyl Groups

2. Understanding organofluorine chemistry. An introduction to the C–F bond

3. Selective Single C(sp3)–F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation

4. Catalytic Defluoroalkylation of Trifluoromethylaromatics with Unactivated Alkenes

5. Selective C–F Functionalization of Unactivated Trifluoromethylarenes

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent Advance in the C−F Bond Functionalization of Trifluoromethyl Aromatic and Carbonyl Compounds;ChemCatChem;2024-01-25

2. A review of frustrated Lewis pair enabled monoselective C–F bond activation;Chemical Science;2024

3. Photoinduced copper-catalyzed C–N coupling with trifluoromethylated arenes;Nature Communications;2023-12-14

4. Frustrated Lewis pair catalyzed C–F activation of α-trifluoromethylstyrenes;Tetrahedron Chem;2023-12

5. Stereoselective Synthesis of Fluoroalkanes via FLP Mediated Monoselective C─F Activation of Geminal Difluoroalkanes;Advanced Science;2023-10-31