Enantioselective synthesis of α,α-difluoro-β-lactams using amino alcohol ligands-Reference-Cited by-同舟云学术

Enantioselective synthesis of α,α-difluoro-β-lactams using amino alcohol ligands

Published:2014 Issue:33 Volume:12 Page:6484-6489
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Tarui Atsushi¹²³,Ikebata Takeshi¹²³,Sato Kazuyuki¹²³,Omote Masaaki¹²³,Ando Akira¹²³

Affiliation:

1. Faculty of Pharmaceutical Sciences

2. Setsunan University

3. Hirakata, Japan

Abstract

A practical and highly enantioselective Reformatsky reaction of ethyl bromodifluoroacetate with imines using a cheap and commercially available amino alcohol ligand is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB01184H

Reference54 articles.

1. Understanding organofluorine chemistry. An introduction to the C–F bond

2. Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

3. Fluorine in Pharmaceuticals: Looking Beyond Intuition

4. Fluorine in health care: Organofluorine containing blockbuster drugs

5. The Unique Role of Fluorine in the Design of Active Ingredients for Modern Crop Protection

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Zinc Enolates: The Reformatsky and Blaise Reactions;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2023

2. Azetidines, Azetines and Azetes: Monocyclic;Comprehensive Heterocyclic Chemistry IV;2022

3. The Asymmetric Difluoro‐Reformatsky Reaction;European Journal of Organic Chemistry;2021-02-19

4. Copper-catalyzed [3 + 1] cyclization of cyclopropenes/diazo compounds and bromodifluoroacetamides: facile synthesis of α,α-difluoro-β-lactam derivatives;Chemical Science;2021

5. Stereoselective Synthesis of Multisubstituted α-fluoro-β-lactams;Current Organic Chemistry;2020-11-18