Optimization, automation and validation of the large-scale radiosynthesis of Al18F tracers in a custom-made automatic platform for high yield

Author:

Liu Zhiguo12345ORCID,Yu Lun6785,Cheng Kai12345,Feng Yabo6785,Qiu Pengfei923105,Gai Yongkang1112131415ORCID,Zhou Ming111617185

Affiliation:

1. Department of PET/CT Center

2. Shandong Cancer Hospital and Institute

3. Shandong First Medical University and Shandong Academy of Medical Sciences

4. Jinan

5. China

6. Department of PET-CT Center

7. Chenzhou No. 1 People's Hospital

8. Chenzhou 423000

9. Breast Cancer Center

10. Jinan 250117

11. Department of Nuclear Medicine

12. Union Hospital

13. Tongji Medical College

14. Huazhong University of Science and Technology

15. Hubei Province Key Laboratory of Molecular Imaging

16. Xiangya Hospital

17. Central South University

18. Changsha 410008

Abstract

A custom-made automatic platform was designed and developed for large scale Al18F tracer synthesis with high yield.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

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