Amidic resonance not a barrier for transamidation of <i>N</i>-pivaloyl activated amides: catalyst, base and additive free conditions-Reference-Cited by-同舟云学术

Amidic resonance not a barrier for transamidation of N-pivaloyl activated amides: catalyst, base and additive free conditions

Published:2023 Issue:23 Volume:21 Page:4760-4765
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Samuel Rajan Ida Angel Priya¹,Rajendran Saravanakumar¹^ORCID

Affiliation:

1. Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology Chennai Campus, Vandalur-Kelambakkam road, Chennai – 600127, Tamil Nadu, India

Abstract

N-Pivaloylation enables amides as reactive substrates for transamidation with a wide array of alkyl amines in the absence of a catalyst, base and additive at room temperature in a short reaction time.

Funder

Vellore Institute of Technology, Chennai

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00418J

Reference33 articles.

1. Highly selective transition-metal-free transamidation of amides and amidation of esters at room temperature

2. Tungsten-Catalyzed Transamidation of Tertiary Alkyl Amides

3. Zn-Catalyzed Nicotinate-Directed Transamidations in Peptide Synthesis