Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors

Published:2019 Issue:4 Volume:10 Page:528-537
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Kildahl-Andersen Geir¹²³⁴⁵,Schnaars Christian¹²³⁴⁵,Prandina Anthony¹²³⁴⁵,Radix Sylvie⁶⁷⁸⁹¹⁰^ORCID,Le Borgne Marc⁶⁷⁸⁹¹⁰^ORCID,Jordheim Lars Petter⁸¹¹¹²¹³¹⁴,Gjøen Tor¹⁵¹⁶³¹⁷⁵^ORCID,Andresen Adriana Magalhães Santos¹⁵¹⁶³¹⁷⁵,Lauksund Silje¹⁸¹⁹²⁰²¹⁵,Fröhlich Christopher¹⁸¹⁹²⁰²¹⁵,Samuelsen Ørjan¹⁸¹⁹²⁰²¹⁵^ORCID,Rongved Pål¹²³⁴⁵,Åstrand Ove Alexander Høgmoen¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry

2. School of Pharmacy

3. University of Oslo

4. 0316 Oslo

5. Norway

6. EA 4446 Bioactive Molecules and Medicinal Chemistry

7. Faculté de Pharmacie – ISPB

8. Université de Lyon

9. Université Lyon 1

10. Lyon cedex 08

11. Université Claude Bernard Lyon 1

12. INSERM 1052

13. CNRS UMR5286

14. Centre Léon Bérard

15. Centre for Integrative Microbial Evolution (CIME)

16. Faculty of Mathematics and Natural Sciences

17. Oslo

18. Norwegian National Advisory Unit on Detection of Antimicrobial Resistance

19. Department of Microbiology and Infection Control

20. University Hospital of North Norway

21. 9038 Tromsø

Abstract

New MBL inhibitor renders resistant Gram negative bacteria susceptible to carbapenems.

Funder

Universitetet i Oslo

Novo Nordisk Fonden

Norges Forskningsråd

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C8MD00578H

Reference35 articles.

1. Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis

2. WHO , in WHO infectious disease report : Removing obstacles to healthy development , 1999

3. WHO , in The evolving threat of antimicrobial resistance : Options for action , 2012

4. WHO , in ANTIMICROBIAL RESISTANCE Global Report on Surveillance , 2014

5. “Stormy waters ahead”: global emergence of carbapenemases

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4. Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates;Journal of Medicinal Chemistry;2022-11-30

5. Dihydroxyphenyl-substituted thiosemicarbazone: A potent scaffold for the development of metallo-β-lactamases inhibitors and antimicrobial;Bioorganic Chemistry;2022-10

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