Catalyst-free decarboxylative deuteration using tailored photoredox-active carboxylic acids-Reference-Cited by-同舟云学术

Catalyst-free decarboxylative deuteration using tailored photoredox-active carboxylic acids

Published:2024 Issue: Volume: Page:
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Liu Shuai¹,Liao Hongze²^ORCID,Chen Bin³^ORCID,Guo Tengyu²,Zhang Zhizhen¹,Lin Houwen²⁴

Affiliation:

1. Ocean College, Zhoushan Campus, Zhejiang University, Zhoushan 316021, China

2. Research Center for Marine Drugs, Department of Pharmacy, Renji Hospital, Clinical Pharmacy college, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China

3. Institute of Marine Biomedicine, Shenzhen Polytechnic University, Shenzhen 518055, China

4. State Key Laboratory of Microbial Metabolism and Ministry of Education Key Laboratory of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China

Abstract

Herein, we introduce a green, catalyst-free method for precise decarboxylative deuteration using tailored photoredox-active acid (PAC) under mild conditions. Mechanistic investigations reveal that PAC simultaneously acts as both reactant and catalyst.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D4GC01134A

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