Enantioselective conjugate addition of cyanide to chalcones catalyzed by a magnesium-Py-BINMOL complex
Author:
Affiliation:
1. Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, and College of Material
2. Chemistry and Chemical Engineering
3. Hangzhou Normal University
4. Hangzhou 310012
5. PR China
Abstract
An efficient asymmetric conjugate addition of trimethylsilyl cyanide (TMSCN) to chalcones, catalyzed by bifunctional Py-BINMOL-Mg complex, with moderate to good enantioselectivities and in good yields, has been realized in this work.
Publisher
Royal Society of Chemistry (RSC)
Subject
Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2015/CY/C5CY01056J
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