Guanidiniocarbonyl-pyrrole-aryl conjugates as inhibitors of human dipeptidyl peptidase III: combined experimental and computational study-Reference-Cited by-同舟云学术

Guanidiniocarbonyl-pyrrole-aryl conjugates as inhibitors of human dipeptidyl peptidase III: combined experimental and computational study

Published:2016 Issue:86 Volume:6 Page:83044-83052
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Matić Josipa¹²³⁴,Šupljika Filip¹²³⁴,Tir Nora¹²³⁴,Piotrowski Patryciusz⁵⁶⁷⁸⁹,Schmuck Carsten⁵⁶⁷⁸⁹,Abramić Marija¹²³⁴,Piantanida Ivo¹²³⁴,Tomić Sanja¹²³⁴

Affiliation:

1. Division of Organic Chemistry and Biochemistry

2. Ruđer Bošković Institute

3. 10000 Zagreb

4. Croatia

5. Institute for Organic Chemistry

6. University of Duisburg-Essen

7. Universitässtrasse 7

8. 45141 Essen

9. Germany

Abstract

Good overlap of the standard DPP III substrate Arg-Arg-2NA (magenta) and the most efficient novel inhibitor (guanidiniocarbonyl-pyrrole-pyrene conjugate, blue-red) in the DPP III binding site.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA16966J

Reference27 articles.

1. Human dipeptidyl peptidase III acts as a post-proline-cleaving enzyme on endomorphins

2. A genomic screen for activators of the antioxidant response element

3. Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination

4. Human dipeptidyl peptidase III: insights into ligand binding from a combined experimental and computational approach

5. Human Dipeptidyl Peptidase III: the Role of Asn406 in Ligand Binding and Hydrolysis

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme;Beilstein Journal of Organic Chemistry;2023-04-26

2. Neuropeptides, substrates and inhibitors of human dipeptidyl peptidase III, experimental and computational study — A new substrate identified;International Journal of Biological Macromolecules;2022-11

3. Experimental and computational evaluation of dipeptidyl peptidase III inhibitors based on quinazolinone-Schiff’s bases;Journal of Biomolecular Structure and Dynamics;2022-09-15

4. Survey of Dipeptidyl Peptidase III Inhibitors: From Small Molecules of Microbial or Synthetic Origin to Aprotinin;Molecules;2022-05-07

5. Coumarin Derivatives Act as Novel Inhibitors of Human Dipeptidyl Peptidase III: Combined In Vitro and In Silico Study;Pharmaceuticals;2021-06-05