Dual-recognition colorimetric sensing of thrombin based on surface-imprinted aptamer

Dual-recognition colorimetric sensing of thrombin based on surface-imprinted aptamer–Fe3O4

Published:2021 Issue:20 Volume:9 Page:4249-4256
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Shen Mingmei¹²³⁴⁵,Wang Yuanyuan¹²³⁴⁵,Kan Xianwen¹²³⁴⁵^ORCID

Affiliation:

1. College of Chemistry and Materials Science

2. Anhui Normal University

3. Wuhu 241000

4. P. R. China

5. The Key Laboratory of Functional Molecular Solids

Abstract

A convenient and effective colorimetric approach was developed for the sensitive and selective detection of thrombin based on blocking the peroxidase-like activity of inner Fe₃O₄ nanoparticles by the adsorption of thrombin in imprinted cavities.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Anhui Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB00565K

Reference55 articles.

1. One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters as peroxidase mimics for colorimetric detection of thrombin

2. Colorimetric determination of thrombin by exploiting a triple enzyme-mimetic activity and dual-aptamer strategy

3. Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer’s Disease

4. Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer’s Disease

5. Thrombin Signaling Contributes to High Glucose-Induced Injury of Human Brain Microvascular Endothelial Cells

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