All-atom MD indicates ion-dependent behavior of therapeutic DNA polymer
Author:
Affiliation:
1. Department of Physics
2. Wake Forest University
3. Winston Salem
4. USA
5. Department of Mathematics and Statistics
6. Department of Cancer Biology
7. Wake Forest University School of Medicine
Abstract
Understanding the efficacy of and creating delivery mechanisms for therapeutic nucleic acids requires understanding structural and kinetic properties which allow these polymers to promote the death of cancerous cells.
Funder
National Institute of General Medical Sciences
National Cancer Institute
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2017/CP/C7CP03479B
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