Total syntheses of wentilactones A and B, and related norditerpene dilactones

Author:

Hou Wu1,Cao Xin2,Xu Peng3ORCID,Yu Biao3

Affiliation:

1. School of Physical Science and Technology, ShanghaiTech University, 100 Haike Road, Shanghai 201210, China

2. Zhongshan Hospital Institute of Clinical Science, Fudan University Shanghai Medical College, 180 Fengling Road, Shanghai 200032, China

3. State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China

Abstract

A divergent approach toward the synthesis of A-ring functionalized tetranorditerpenoid dilactones has been developed, employing 3β-hydroxydilactone 6 as a common precursor which is readily derived from (S)-Wieland–Miescher ketone.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Science and Technology Commission of Shanghai Municipality

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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