A self-assembled peptidic nanomillipede to fabricate a tuneable hybrid hydrogel

Author:

Liu Jianhui1234ORCID,Ni Rong12345ORCID,Chau Ying1234ORCID

Affiliation:

1. Department of Chemical and Biological Engineering

2. the Hong Kong University of Science and Technology

3. Clear Water Bay

4. Hong Kong

5. Institute for Advanced Study

Abstract

Peptidic ‘nanomillipede’, consisting of worm-like nanoscale ‘body’ and cysteine-terminated ‘legs’, was synthesized, tuned (with ultrasound) and utilized to crosslink the vinyl sulfone-modified dextran to form hybrid hydrogels with soft-tissue mimicking tuneable mechanical strength, self-healing property, and tuneable shear-thinning property, thereby indicating their potential use in tissue engineering and drug delivery.

Funder

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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