Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming-Reference-Cited by-同舟云学术

Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming

Published:2016 Issue:7 Volume:12 Page:2296-2303
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Liu Jing¹²³⁴⁵,Xiao Hai-Tao⁵⁶⁴⁷⁸,Wang Hong-Sheng¹²³⁴,Mu Huai-Xue⁵⁶⁴,Zhao Ling⁵⁶⁴,Du Jun¹²³⁴,Yang Depo¹²³⁴,Wang Dongmei¹²³⁴,Bian Zhao-Xiang⁵⁶⁴,Lin Shu-Hai⁵⁶⁴⁹¹⁰

Affiliation:

1. School of Pharmaceutical Sciences

2. Sun Yat-Sen University

3. Guangzhou 510006

4. China

5. School of Chinese Medicine

6. Hong Kong Baptist University

7. School of Pharmacy

8. Guizhou Medicial University

9. Department of Biochemistry and Molecular Cell Biology

10. Shanghai Key Laboratory for Tumor Microenvironment and Inflammation

Abstract

Halofuginone inhibits both HIF-1alpha and incomplete FAO to reduce the inflammatory response in DSS-induced colitis.

Funder

Research Grants Council, University Grants Committee, Hong Kong

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MB/C6MB00154H

Reference34 articles.

1. Inflammatory Bowel Disease

2. Experimental colitis models: Insights into the pathogenesis of inflammatory bowel disease and translational issues

3. Lipidomic Profiling in Inflammatory Bowel Disease

4. Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD

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