Toxicity of metal–organic framework nanoparticles: from essential analyses to potential applications

Author:

Ettlinger Romy1ORCID,Lächelt Ulrich23ORCID,Gref Ruxandra4ORCID,Horcajada Patricia5ORCID,Lammers Twan6ORCID,Serre Christian7ORCID,Couvreur Patrick8ORCID,Morris Russell E.1ORCID,Wuttke Stefan910ORCID

Affiliation:

1. School of Chemistry, University of St. Andrews, St. Andrews, UK

2. Department of Pharmacy and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität München, Munich, Germany

3. Division of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Vienna, Austria

4. Institut de Sciences Moléculaires d'Orsay, Université Paris Saclay, Paris, France

5. Madrid Institute for Advanced Studies, Madrid, Spain

6. Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany

7. Département de Chimie, Ecole Normale Supérieure de Paris, Paris, France

8. Institut Galien Paris-Sud, Université Paris Saclay, Paris, France

9. Ikerbasque, Basque Foundation for Science, Bilbao, Spain

10. Basque Center for Materials, UPV/EHU Science Park, Leioa, Spain

Abstract

This tutorial review highlights the key aspects of nanotoxicity and the importance of its systematic assessment for metal–organic framework (MOF) nanoparticles to pave the way towards their potential applications in a safe and sustainable manner.

Funder

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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