Detection of analytes in mitochondria without interference from other sites based on an innovative ratiometric fluorophore-Reference-Cited by-同舟云学术

Detection of analytes in mitochondria without interference from other sites based on an innovative ratiometric fluorophore

Published:2018 Issue:24 Volume:9 Page:5461-5466
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ren Tian-Bing¹²³⁴⁵,Zhang Qian-Ling¹²³⁴⁵,Su Dongdong²⁶⁷⁵,Zhang Xing-Xing¹²³⁴⁵,Yuan Lin¹²³⁴⁵^ORCID,Zhang Xiao-Bing¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics

2. College of Chemistry and Chemical Engineering

3. Hunan University

4. Changsha 410082

5. PR China

6. Tianjin University of Technology

7. Tianjin 300384

Abstract

A new strategy that integrates the targeting group and response moiety together for the preparation of mitochondrial probe was developed. Bioimaging studies have shown that for the first time, the newly designed probe HDFL-Cys can first accumulate in mitochondria and then react with the analyte.

Funder

National Natural Science Foundation of China

Hunan Provincial Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SC/C8SC01673A

Reference46 articles.

1. Autophagy in the Pathogenesis of Disease

2. Mitochondria: More Than Just a Powerhouse