Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles
Author:
Affiliation:
1. Department of Medicine
2. University of Chicago
3. Chicago, USA
4. Institute for Molecular Engineering
5. Argonne National Laboratory
6. Lemont, USA
7. Department of Pathology
Abstract
Polyelectrolyte complex micelles have great potential as gene delivery vehicles because of their ability to encapsulate charged nucleic acids forming a core by neutralizing their charge, while simultaneously protecting the nucleic acids from non-specific interactions and enzymatic degradation.
Funder
American Heart Association
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2014/TB/C4TB00977K
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