The holy grail of pyrene-based surface ligands on the sensitivity of graphene-based field effect transistors

Author:

Mishyn Vladyslav1,Hugo Adrien1ORCID,Rodrigues Teresa2,Aspermair Patrik2ORCID,Happy Henri1,Marques Leonel3,Hurot Charlotte3,Othmen Riadh3,Bouchiat Vincent3,Boukherroub Rabah1,Knoll Wolfgang24,Szunerits Sabine1ORCID

Affiliation:

1. Univ. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 – IEMN, F-59000 Lille, France

2. AIT Austrian Institute of Technology GmbH, Biosensor Technologies, 3430 Tulln, Austria

3. GRAPHEAL SAS, 25 avenue des Martyrs, 38042 Grenoble CEDEX 09, France

4. Department of Scientific Coordination and Management, Danube Private University, A-3500 Krems, Austria

Abstract

The use of pyrene–maleimide as an optimal surface ligand for GFET biosensor applications is proposed. With an immersion time of 2 h, cardiac troponin I (cTnI) could be sensed down to 22 ± 1 pg mL−1.

Funder

Agence Nationale de la Recherche

Centre National de la Recherche Scientifique

Publisher

Royal Society of Chemistry (RSC)

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