Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin-Reference-Cited by-同舟云学术

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Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin

Published:2015 Issue:5 Volume:6 Page:788-794
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Madadi Nikhil R.¹²³⁴⁵,Zong Hongliang⁶⁷⁸⁹⁵,Ketkar Amit¹⁰¹¹³⁴⁵,Zheng Chen¹²³⁴⁵,Penthala Narsimha R.¹²³⁴⁵,Janganati Venumadhav¹²³⁴⁵,Bommagani Shobanbabu¹²³⁴⁵,Eoff Robert L.¹⁰¹¹³⁴⁵,Guzman Monica L.⁶⁷⁸⁹⁵,Crooks Peter A.¹²³⁴⁵

Affiliation:

1. Department of Pharmaceutical Sciences

2. College of Pharmacy

3. University of Arkansas for Medical Sciences

4. Little Rock

5. USA

6. Division of Hematology and Medical Oncology

7. Department of Medicine

8. Weill Medical College of Cornell University

9. New York

10. Department of Biochemistry and Molecular Biology

11. College of Medicine

Abstract

Novel resveratrol analogues have been synthesized and evaluated for their anticancer activities against a panel of 60 human cancer cell lines.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C4MD00478G

Reference29 articles.

1. Vascular Targeting Agents as Cancer Therapeutics

2. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain

3. Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines

4. Synthesis and biological evaluation of 3-(trimethoxyphenyl)-2(3H)-thiazole thiones as combretastatin analogs

5. Preparation of 4,5 disubstituted-2H-1,2,3-triazoles from (Z)-2,3-diaryl substituted acrylonitriles

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