IFN-γ/SrBG composite scaffolds promote osteogenesis by sequential regulation of macrophages from M1 to M2

Author:

Luo Man12345ORCID,Zhao Fujian6785,Liu Lu12345ORCID,Yang Zhen12345,Tian Ting945103,Chen Xiaoyu12345,Cao Xiaodong12345,Chen Dafu1112131415,Chen Xiaofeng12345

Affiliation:

1. Department of Biomedical Engineering

2. School of Materials Science and Engineering

3. South China University of Technology

4. Guangzhou

5. China

6. Stomatological Hospital

7. Southern Medical University

8. Guangzhou 510280

9. National Engineering Research Center for Tissue Restoration and Reconstruction

10. Key Laboratory of Biomedical Engineering of Guangdong Province

11. Laboratory of Bone Tissue Engineering

12. Beijing Laboratory of Biomedical Materials

13. Beijing Research Institute of Orthopaedics and Traumatology

14. Beijing JiShuiTan Hospital

15. Beijing

Abstract

The macrophage-dominated bone immune response plays an important role in osteogenesis of bone defects.

Funder

Natural Science Foundation of Guangdong Province

National Key R&D Program of China

National Natural Science Foundation of China

Beijing Municipal Bureau of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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