Chelation-assisted iridium-catalyzed hydroalkenylation and hydroarylation/cyclization with conjugated trienes

Author:

Liao Yilei1,Zhang Cheng1,Wang Yini1,Hu Yibu2,Ding Liyuan1,Zhong Liangjun3,Zhong Guofu14ORCID,Zhang Jian13ORCID

Affiliation:

1. College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou, 311121 Zhejiang, China

2. College of Information Science & Technology, Beijing University of Chemical Technology, Beijing 100029, China

3. Department of Stomatology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, 310015, China

4. Department of Chemistry, Eastern Institute for Advanced Study, Ningbo 315200, Zhejiang, China

Abstract

While Ir-catalyzed hydroalkenylation of 1,3,5-trienes by alkenyl C–H activation of acrylamides delivers 1,4,6-trienes, benzamides and 1,3,5-trienes undergo tandem hydroarylation and intramolecular 1,2-addition to give tetrahydroisoquinolinones.

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Enantioselective and Regiodivergent Synthesis of Dihydro-1,2-oxazines from Triene-Carbamates via Chiral Phosphoric Acid-Catalysis;Journal of the American Chemical Society;2023-11-27

2. Catalytic Addition of C–H Bonds Across C–C π-Bonds;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2023

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