Synthesis of enantiopure 1,2,3-triazolylidene-type mesoionic carbene (MIC) conjugate acids featuring a rigid bicyclic scaffold-Reference-Cited by-同舟云学术

Synthesis of enantiopure 1,2,3-triazolylidene-type mesoionic carbene (MIC) conjugate acids featuring a rigid bicyclic scaffold

Published:2024 Issue:8 Volume:11 Page:2178-2181
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Dočekal Vojtěch¹²^ORCID,Melaimi Mohand²^ORCID,Petrželová Simona³,Veselý Jan¹,Yan Xiaoyu⁴^ORCID,Bertrand Guy²^ORCID

Affiliation:

1. Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 2030/8, 128 43 Prague 2, Czech Republic

2. UCSD-CNRS Joint Research Laboratory (IRL3555), Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA-92093-0343, USA

3. Department of Chemistry Education, Faculty of Science, Charles University, Hlavova 2030/8, 128 43 Prague 2, Czech Republic

4. Key Laboratory of Advanced Light Conversion Materials and Biophotonics, Department of Chemistry, Renmin University of China, Beijing, 100872, China

Abstract

Chiral NHCs have found numerous applications as ligands for transition metals and in their own right for asymmetric catalysis. We report a synthetic route from l-malic acid to enantiopure 1,2,3-triazoliums with the chiral center in a fused ring.

Funder

National Science Foundation

Grantová Agentura České Republiky

Fulbright Association

Univerzita Karlova v Praze

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00269E

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