Characterization of the degradation products of bambuterol using LCMS-QTOF and NMR-Reference-Cited by-同舟云学术

Characterization of the degradation products of bambuterol using LCMS-QTOF and NMR

Published:2015 Issue:18 Volume:7 Page:7659-7673
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Abiramasundari A.¹²³⁴⁵,Sudarsanam V.¹²³⁴,Vasu Kamala K.¹²³⁴

Affiliation:

1. Department of Medicinal Chemistry

2. B. V. Patel PERD Centre

3. Ahmedabad

4. India

5. Nirma University

Abstract

A systematic forced degradation study of bambuterol was carried out according to ICH guidelines. Twelve degradation products of bambuterol were identified and characterized. Plausible mechanisms of formation of the degradation products are discussed.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AY/C5AY00569H

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