Alkylated histidine based short cationic antifungal peptides: synthesis, biological evaluation and mechanistic investigations-Reference-Cited by-同舟云学术

Alkylated histidine based short cationic antifungal peptides: synthesis, biological evaluation and mechanistic investigations

Published:2016 Issue:48 Volume:6 Page:41951-41961
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mittal Sherry¹²³⁴,Kaur Sarabjit¹²³⁴,Swami Anuradha⁵⁶²³⁴,Maurya Indresh K.⁷²³⁴,Jain Rahul⁸⁹¹⁰⁴,Wangoo Nishima⁵⁶²³⁴,Sharma Rohit K.¹²³⁴

Affiliation:

1. Department of Chemistry & Centre for Advanced Studies in Chemistry

2. Panjab University

3. Chandigarh-160014

4. India

5. Department of Applied Sciences

6. University Institute of Engineering & Technology (U.I.E.T.)

7. Department of Microbial Biotechnology

8. Department of Medicinal Chemistry

9. National Institute of Pharmaceutical Education & Research (NIPER)

10. S.A.S. Nagar

Abstract

Novel antifungal peptides are described with some peptides exhibiting selective activity againstC. neoformans. Cytotoxicity and mechanistic studies reveal their applicability as effective antimicrobials with less susceptibility to drug resistance.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA05883C

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