Bioisosteric modification of known fucosidase inhibitors to discover a novel inhibitor of α-l-fucosidase-Reference-Cited by-同舟云学术

Bioisosteric modification of known fucosidase inhibitors to discover a novel inhibitor of α-l-fucosidase

Published:2017 Issue:6 Volume:7 Page:3563-3572
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Bathula Chandramohan¹²³⁴,Ghosh Shreemoyee⁵⁶⁷⁴,Hati Santanu¹²³⁴,Tripathy Sayantan⁸²³⁴,Singh Shailja⁸²³⁴,Chakrabarti Saikat⁵⁶⁷⁴,Sen Subhabrata¹²³⁴

Affiliation:

1. Department of Chemistry

2. School of Natural Sciences

3. Shiv Nadar University

4. India

5. Structural Biology and Bio-Informatics Division

6. CSIR-Indian Institute of Chemical Biology

7. Kolkata

8. Department of Life Sciences

Abstract

Hydantoin, thiohydantoin and pyridone analogs as α-l-fucosidase inhibitors through bioisosteric modification of known bovine α-l-fucosidase inhibitors.

Funder

Council for Scientific and Industrial Research

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA24939F

Reference28 articles.

1. Importance of glycosidases in mammalian glycoprotein biosynthesis

2. Glycosidase inhibitors: update and perspectives on practical use

3. Lysosomal metabolism of glycoproteins

4. Fungal enzyme sets for plant polysaccharide degradation

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