Synthesis and biological evaluation of indazole derivatives as anti-cancer agents-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of indazole derivatives as anti-cancer agents

Published:2021 Issue:26 Volume:11 Page:15675-15687
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wei Wei¹²³⁴⁵,Liu Zhihao¹²³⁴⁵,Wu Xiuli¹²³⁴⁵,Gan Cailing¹²³⁴⁵,Su Xingping¹²³⁴⁵,Liu Hongyao¹²³⁴⁵,Que Hanyun¹²³⁴⁵,Zhang Qianyu⁶⁷⁸⁴⁵,Xue Qiang¹²³⁴⁵,Yue Lin¹²³⁴⁵,Yu Luoting¹²³⁴⁵^ORCID,Ye Tinghong¹²³⁴⁵^ORCID

Affiliation:

1. Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer

2. State Key Laboratory of Biotherapy and Cancer Center

3. West China Hospital

4. Sichuan University

5. Chengdu

6. Research Center for Public Health & Preventive Medicine

7. West China School of Public Health & Healthy Food Evaluation Research Center

8. West China Fourth Hospital

Abstract

One of the synthesized indazole derivatives, 2f, displayed inhibitory activities against proliferation, migration and invasion of breast cancer cell line 4T1, with the potential of inducing cell apoptosis, and suppressing tumor growth in vivo.

Funder

National Natural Science Foundation of China

West China Hospital, Sichuan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA01147B

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1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

2. Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape