A fluorogenic RNA aptamer nanodevice for the low background imaging of mRNA in living cells-Reference-Cited by-同舟云学术

A fluorogenic RNA aptamer nanodevice for the low background imaging of mRNA in living cells

Published:2022 Issue:9 Volume:58 Page:1354-1357
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Xu Tingting¹,Sun Yao¹,Yu Sha²^ORCID,Wu Shaojun¹,Su Yu¹,Tian Ye¹³^ORCID,Zhou Yuanzhen²^ORCID,Zhu Jun-Jie¹²^ORCID

Affiliation:

1. State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China

2. School of Chemistry and Chemical Engineering, Xi’an University of Architecture and Technology, Xi’an 710055, China

3. Shenzhen Research Institute of Nanjing University, Shenzhen 518000, China

Abstract

A fluorogenic RNA aptamer nanodevice was developed that integrated NIR-light control and an entropy-driven RNA amplifier for the NIR-assisted imaging of low-abundance TK1 mRNA in living cells with a low background signal and high sensitivity.

Funder

National Natural Science Foundation of China

Shenzhen International Cooperation Research Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D1CC06582C

Reference25 articles.

1. In Situ Amplification‐Based Imaging of RNA in Living Cells

2. Imaging intracellular RNA distribution and dynamics in living cells

3. Toehold-initiated Rolling Circle Amplification for Visualizing Individual MicroRNAs In Situ in Single Cells

4. Highly specific imaging of mRNA in single cells by target RNA-initiated rolling circle amplification

5. Branched Hybridization Chain Reaction Circuit for Ultrasensitive Localizable Imaging of mRNA in Living Cells

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