Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery-Reference-Cited by-同舟云学术

Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery

Published:2015 Issue:17 Volume:51 Page:3645-3648
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Garg P.¹²³⁴,Pandey S.¹²³⁴,Seonwoo Hoon¹²³⁴,Yeom Seungmin¹²³⁴,Choung Yun-Hoon⁵⁶⁷⁴,Cho Chong-Su⁸²⁹⁴,Choung Pill-Hoon¹⁰¹¹²¹²⁴,Hoon Chung Jong¹²³⁴¹³

Affiliation:

1. Department of Biosystems & Biomaterials Science and Engineering

2. Seoul National University

3. Seoul

4. Republic of Korea

5. Department of Otolaryngology

6. Ajou University School of Medicine

7. Suwon 443-749

8. Department of Agricultural Biotechnology

9. Seoul 151-921

10. Department of Oral and Maxillofacial Surgery and Dental Research Institute

11. School of Dentistry

12. Seoul 110-774

13. Research Institute for Agriculture and Life Sciences

Abstract

We report that the incorporation of a hyperosmotic molecule, dixylitol, into the backbone of a delivery vector can enhance its blood brain barrier transmigration.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C4CC09871D

Reference30 articles.

1. Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology

2. Nanotechnology approach for drug addiction therapy: Gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons

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