Structural switch from a multistranded G-quadruplex to single strands as a consequence of point mutation in the promoter of the human GRIN1 gene
Author:
Affiliation:
1. Nucleic Acids Research Laboratory
2. Department of Chemistry
3. University of Delhi
4. Delhi
5. India
6. CSIR-Institute of Genomics and Integrative Biology
Abstract
Formation of a multistranded G-quadruplex in a sequence with point mutation in the promoter of the humanGRIN1gene associated with schizophrenia.
Funder
University of Delhi
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2017/MB/C7MB00360A
Reference81 articles.
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4. Non-B DNA structure-induced genetic instability and evolution
5. Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA
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