Label-free plasmonic-based biosensing using a gold nanohole array chip coated with a wafer-scale deposited WS2monolayer

Author:

Kang Lixing123ORCID,Zhang Yan45,Gong Qian3,Das Chandreyee Manas12,Shao Huilin45,Poenar Daniel Puiu12,Coquet Philippe16,Yong Ken-Tye7ORCID

Affiliation:

1. CINTRA CNRS/NTU/THALES, UMI 3288, Research Techno Plaza, 50 Nanyang Drive, Border X Block, Singapore 637553, Singapore

2. School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore

3. Division of Advanced Materials, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China

4. Institute for Health Innovation & Technology, National University of Singapore, Singapore 117583, Singapore

5. Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore 117583, Singapore

6. Institut d’Electronique, de Microélectronique et de Nanotechnologie (IEMN), CNRS UMR 8520 – Université de Lille 1, Villeneuve d’Ascq 59650, France

7. The University of Sydney Nano Institute, The University of Sydney, Sydney 2006, New South Wales, Australia

Abstract

This paper reports a novel plasmonic sensor chip made up of a gold nanohole array chip coated with a WS2monolayer, which is then functionalized for the detection of protein–protein interactions.

Funder

Agence Nationale de la Recherche

National Research Foundation Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine

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