Development of a synthetic equivalent of α,α-dicationic acetic acid leading to unnatural amino acid derivatives <i>via</i> tetrafunctionalized methanes-Reference-Cited by-同舟云学术

Development of a synthetic equivalent of α,α-dicationic acetic acid leading to unnatural amino acid derivatives via tetrafunctionalized methanes

Published:2022 Issue:11 Volume:20 Page:2282-2292
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Asahara Haruyasu¹²^ORCID,Bonkohara Atsushi¹,Takagi Masaya¹,Iwai Kento¹³^ORCID,Ito Akitaka¹³^ORCID,Yoshioka Kotaro⁴,Tani Shinki⁴,Umezu Kazuto⁴,Nishiwaki Nagatoshi¹³^ORCID

Affiliation:

1. School of Environmental Science and Engineering, Kochi University of Technology, Tosayamada, Kami, Kochi 782-8502, Japan

2. Graduate School of Pharmaceutical Sciences, Osaka University, Yamadaoka 1-6, Suita, Osaka 565-0871, Japan

3. Research Center for Molecular Design, Kochi University of Technology, Tosayamada, Kami, Kochi 782-8502, Japan

4. Kumiai Chemical Industry Co. Ltd., Nakanogo, Fuji, Shizuoka 421-3306, Japan

Abstract

DEMO serves as a synthetic equivalent of dicationic acetic acid to facilitate nucleophilic introduction of two kinds of substituents via N-acylimine, which affords tryptophan homologs.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D1OB02482E

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