Cetuximab-Ag2S quantum dots for fluorescence imaging and highly effective combination of ALA-based photodynamic/chemo-therapy of colorectal cancer cells

Author:

Hashemkhani Mahshid1,Demirci Gozde1,Bayir Ali1,Muti Abdullah2,Sennaroglu Alphan123ORCID,Mohammad Hadi Layla4ORCID,Yaghini Elnaz4,Loizidou Marilena4,MacRobert Alexander J.4,Yagci Acar Havva15ORCID

Affiliation:

1. Koc University, Graduate School of Materials Science and Engineering, Rumelifeneri Yolu, Sariyer, 34450, Istanbul, Turkey

2. Koc University, Departments of Physics and Electrical-Electronics Engineering, Rumelifeneri Yolu, Sariyer 34450, Istanbul, Turkey

3. Koc University, KUYTAM, Rumelifeneri Yolu, Sariyer 34450, Istanbul, Turkey

4. Division of Surgery and Interventional Science, Centre for Nanomedicine and Surgical Theranostics, University College London, Royal Free Campus, Rowland Hill St, London NW3 2PE, UK

5. Koc University, Department of Chemistry, Rumelifeneri Yolu, Sariyer 34450, Istanbul, Turkey

Abstract

Highly effective and selective killing of EGFR(+)-colorectal cancer cell lines was achieved with targeted PDT and PDT/chemotherapy combination using theranostic nanoparticles.

Funder

British Council

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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