Synthesis, solid state self-assembly driven by antiparallel π⋯π stacking and {⋯H–C–C–F}<sub>2</sub>dimer synthons, and<i>in vitro</i>acetyl cholinesterase inhibition activity of phenoxy pendant isatins-Reference-Cited by-同舟云学术

Synthesis, solid state self-assembly driven by antiparallel π⋯π stacking and {⋯H–C–C–F}₂dimer synthons, andin vitroacetyl cholinesterase inhibition activity of phenoxy pendant isatins

Published:2022 Issue:3 Volume:12 Page:1788-1796
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mehreen Saba¹,Ullah Aman²^ORCID,Nadeem Humaira³,Dege Necmi⁴^ORCID,Naseer Muhammad Moazzam¹^ORCID

Affiliation:

1. Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan

2. Department of Agricultural, Food and Nutritional Science, 4-10 Agriculture/Forestry Centre, University of Alberta, Edmonton, AB, T6G 2P5, Canada

3. Department of Pharmaceutical Chemistry, Riphah Institute of Pharmaceutical Sciences, Riphah International University, G-7/4, Islamabad, Pakistan

4. Ondokuz Mayıs University, Faculty of Arts and Sciences, Department of Physics, Kurupelit, 55139, Samsun, Turkey

Abstract

The phenoxy pendant isatins were observed to be highly potent inhibitors of acetylcholinesterase. In addition, the solid-state structure of a phenoxy pendant isatin showed an intriguing 1D-supramolecular self-assembled structure.

Funder

Academy of Sciences for the Developing World

Higher Education Commission, Pakistan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D1RA08286H

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