Three-component cascade reaction of 3-ketonitriles, 2-unsubstituted imidazole N-oxides, and aldehydes

Author:

Uvarova Ekaterina S.1ORCID,Kutasevich Anton V.1ORCID,Lipatov Egor S.23ORCID,Pytskii Ivan S.4,Raitman Oleg A.1ORCID,Selivantev Yuriy M.1ORCID,Mityanov Vitaly S.1ORCID

Affiliation:

1. Mendeleev University of Chemical Technology, Miusskaya Sq., 9, Moscow 125047, Russian Federation

2. A.N. Nesmeyanov Institute of Organoelement Compounds Russian Academy of Sciences, Vavilov str. 28/1, 119334 Moscow, Russian Federation

3. Higher Chemical College of Russian Academy of Sciences, D.I. Mendeleev University of Chemical Technology of Russia, Miusskaya pl. 9, 125047, Moscow, Russian Federation

4. A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Academy of Sciences, Leninsky Prospect 31 bldg. 4, 119071 Moscow, Russian Federation

Abstract

A three-component condensation of imidazole N-oxides, 3-ketonitriles and aldehydes was developed. Mechanistic details were revealed using DFT calculations.

Funder

Ministry of Science and Higher Education of the Russian Federation

Publisher

Royal Society of Chemistry (RSC)

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