A urinary metabolomics (GC-MS) strategy to evaluate the antidepressant-like effect of chlorogenic acid in adrenocorticotropic hormone-treated rats-Reference-Cited by-同舟云学术

A urinary metabolomics (GC-MS) strategy to evaluate the antidepressant-like effect of chlorogenic acid in adrenocorticotropic hormone-treated rats

Published:2018 Issue:17 Volume:8 Page:9141-9151
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhao Le¹²³⁴^ORCID,Zhang Zixu¹²³⁴⁵,Zhou Mingmei¹²³⁴⁶^ORCID,Gou Xiaojun⁷⁸²⁹⁴,Zeng Yang¹⁰¹¹¹²⁴⁶,Song Jing¹²³⁴,Ma Weini¹²³⁴,Xu Ying¹³²³⁴^ORCID

Affiliation:

1. Center for Chinese Medicine Therapy and Systems Biology

2. Shanghai University of Traditional Chinese Medicine

3. Shanghai 201203

4. China

5. College of Chinese Pharmacy

6. Key Laboratory of Medicinal Animal and Plant Resources in Qinghai-Tibet Plateau

7. Central Laboratory

8. Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine of Shanghai

9. Shanghai 201999

10. College of Life Science

11. Qinghai Normal University

12. Xining

13. Department of Physiology

Abstract

Chlorogenic acid showed antidepressant-like activity in chronic ACTH-treated rats, providing a potential drug candidate for prevention and treatment of tricyclic antidepressant treatment-resistant depression. Related metabolic pathways were shown.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA00074C

Reference66 articles.

1. Antidepressants and the Risk of Suicidal Behaviors

2. The role of glutamate in mood disorders: Results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects

3. Review: Chinese herbs as alternatives to antibiotics in feed for swine and poultry production: Potential and challenges in application

4. A review of the bioactivity of coffee, caffeine and key coffee constituents on inflammatory responses linked to depression

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