Benzoates as photosensitization catalysts and auxiliaries in efficient, practical, light-powered direct C(sp<sup>3</sup>)

Benzoates as photosensitization catalysts and auxiliaries in efficient, practical, light-powered direct C(sp³)–H fluorinations

Published:2022 Issue:47 Volume:13 Page:14041-14051
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yakubov Shahboz¹^ORCID,Stockerl Willibald J.¹^ORCID,Tian Xianhai¹,Shahin Ahmed¹²^ORCID,Mandigma Mark John P.¹^ORCID,Gschwind Ruth M.¹^ORCID,Barham Joshua P.¹^ORCID

Affiliation:

1. Fakultät für Chemie und Pharmazie, Universität Regensburg, 93040 Regensburg, Germany

2. Chemistry Department, Faculty of Science, Benha University, 13518 Benha, Egypt

Abstract

Benzoates serve as catalysts or auxiliaries for photochemical EnT radical C(sp3)–H fluorinations. The auxiliary markedly increases scope and efficiency, enabling reactions of free alcohols, amines, and allowing rapid gram-scale fluorinations in air.

Funder

Alexander von Humboldt-Stiftung

Bundesministerium für Bildung und Forschung

Deutscher Akademischer Austauschdienst

Elitenetzwerk Bayern

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC05735B