Cytosine-functionalized bioinspired hydrogels for ocular delivery of antioxidant transferulic acid-Reference-Cited by-同舟云学术

Cytosine-functionalized bioinspired hydrogels for ocular delivery of antioxidant transferulic acid

Published:2020 Issue:4 Volume:8 Page:1171-1180
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Varela-Garcia Angela¹²³⁴⁵,Concheiro Angel¹²³⁴⁵^ORCID,Alvarez-Lorenzo Carmen¹²³⁴⁵^ORCID

Affiliation:

1. Departamento de Farmacología

2. Farmacia y Tecnología Farmacéutica

3. I+D Farma

4. Facultad de Farmacia and Health Research Institute of Santiago de Compostela (IDIS)

5. Universidade de Santiago de Compostela

Abstract

Cytosine endows HEMA hydrogels with affinity for antioxidants, such as transferulic acid (TA), having complementary hydrogen bonding and π–π stacking ability. The affinity was reinforced with EGPEM, suggesting molecular cleft-like binding sites.

Funder

Ministerio de Economía y Competitividad

Agencia Estatal de Investigación

Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/C9BM01582E

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