The lipid platform increases the activity of STING agonists to synergize checkpoint blockade therapy against melanoma
Author:
Affiliation:
1. Department of Hematology and Oncology
2. Hwa Mei Hospital
3. University of Chinese Academy of Sciences
4. Ningbo 315000
5. China
6. Department of Dermatology
7. Ningbo
8. Maternity & Child Health Hospital
9. Yuyao
Abstract
The response rate to PD-1/PD-L1 immune checkpoint inhibition (ICI) therapy in melanoma remains low due to the immunosuppressive tumor microenvironment.
Funder
Natural Science Foundation of Ningbo
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM00870B
Reference27 articles.
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4. Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
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