Optimal synthesis conditions for NBF-modified 8,13-dihydroberberine derivatives-Reference-Cited by-同舟云学术

Optimal synthesis conditions for NBF-modified 8,13-dihydroberberine derivatives

Published:2024 Issue:1 Volume:48 Page:268-280
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Zagrebaev A. D.¹^ORCID,Butova V. V.²,Guda A. A.¹,Chapek S. V.¹,Burov O. N.³,Kurbatov S. V.³,Vinyukova E. Yu.⁴,Neganova M. E.⁴,Aleksandrova Yu. R.⁴,Nikolaeva N. S.⁴,Demidov O. P.⁵,Soldatov A. V.¹

Affiliation:

1. The Smart Materials Research Institute, Southern Federal University, 344090 Rostov-on-Don, Russia

2. Institute of General and Inorganic Chemistry Bulgarian Academy of Sciences, Sofia, Bulgaria

3. Faculty of Chemistry, Southern Federal University, 344090 Rostov-on-Don, Russia

4. Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Severnij Pr. 1, Chernogolovka 142432, Russia

5. Department of Chemistry, North Caucasus Federal University, Pushkin st. 1, Stavropol, 355009, Russia

Abstract

We developed a microfluidic synthesis with UV-Vis diagnostics using a 3D printed chip for 8,13-disubstituted berberines. This system yielded up to 30% higher product yields with high antioxidant activity compared to traditional batch synthesis.

Funder

Southern Federal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ04562E

Reference99 articles.

1. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine

2. Traditional Chinese Medicine in Treatment of Metabolic Syndrome

3. Hypoglycemic herbs and their action mechanisms

4. Efficacy of berberine in patients with type 2 diabetes mellitus

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